
November 2003 From University of California - San Diego Conference to highlight medical advances resulting from 50 years of DNA knowledge In celebration of the 50th anniversary of the description of DNA structure by James Watson and Francis Crick, the Gene Therapy Program at the University of California, San Diego (UCSD) School of Medicine and the journal, Science, will bring together many of the world renowned scientists who have spearheaded the era of molecular medicine.Titled "A Celebration of 50 Years in Medicine," the symposium will be held Nov. 14-15 at the Price Center Theater on the UCSD campus in La Jolla, California. Information is available at 858-534-3940 or [email protected]. Speakers will describe the impact of the DNA findings on real-world medical treatment, according to symposium coordinator Theodore Friedmann, M.D., UCSD professor of pediatrics; director, UCSD Program in Human Gene Therapy; and chair, Recombinant DNA Advisory Committee of the National Institutes of Health. Among the presenters will be Francis Collins, MD, PhD, director of the National Human Genome Research Institute, which recently announced the successful completion of the Human Genome Project; J. Craig Venter, PhD, president of The Center for the Advancement of Genomics and head of the private group that sequenced most of the human genome; Sir David Weatherall, a pioneering researcher in molecular genetics; Margaret Liu, MD, whose investigations in plasmid DNA-based vaccines has helped immunologists attack diseases such as cancer and AIDS; Janet Rowley, MD, Lasker Prize recipient and prominent cancer researcher; Stuart Orkin, MD, a specialist in stem cell research; and Nobel Prize winners J. Michael Bishop, MD, UC San Francisco, and the Salk Institute's Sydney Brenner, PhD and Renato Dulbecco, MD. In an article noting the 50th anniversary, the Los Angeles Times commented that without understanding the structure of DNA, there would be no biotech industry, no Human Genome Project, "not a whisper of a chance for stem-cell therapy, and oceans of ignorance about the workings of our bodies in sickness and in health." While many of the celebrations held this year have focused on the science surrounding the discovery 50 years ago, the UCSD symposium will emphasize the translation of genetic and genomic knowledge to the patient's bedside. Topics and speakers will be: Phenotype-Genotype Relationships in Human Disease David Weatherall, FRS Weatherall Institute for Molecular Medicine University of Oxford, United Kingdom Disease Models Session Chair: Renato Dulbecco, MD Professor The Salk Institute La Jolla, California Mouse Models of Human Disease: From Cancer to Psychiatric Disorders Mario Capecchi, Ph.D. Professor of Human Genetics and Investigator, Howard Hughes Medical Institute University of Utah School of Medicine Modeling the Molecular Pathogenesis of Cancer J. Michael Bishop, MD Chancellor University of California, San Francisco Searching for Breast Cancer Genes: Families, Maps, and Sequences Marie-Claire King, PhD Division of Medical Genetics University of Washington, Seattle Comparative Genomics Towards Gene-based Medicine And Session Chair, Gene-based Medicine Therapy and Prevention Yoshiyuki Sakaki, PhD Professor, Institute of Medical Science The University of Tokyo, Japan Rare and Common Disease Genes in a Population: From Diagnosis to Prevention Leena Peltonen, MD, PhD Department of Medical Genetics & Molecular Medicine And National Public Health Institute of Finland Helsinki Finland Genetics of Neurodevelopmental Disorders Anthony P. Monaco, MD, PhD University of Oxford Wellcome Trust Centre for Human Genetics United Kingdom Gene-based Therapy and Prevention Session Chair: Janet Rowley, MD Department of Medicine, Molecular Genetics and Cell Biology The University of Chicago Impact of Imatinib Mesyiate on the Treatment of CML Brian Druker, MD Investigator, Howard Hughes Medical Institute JELD-WEN Chair of Leukemia Research Oregon Health & Science University, Portland From Disease Mechanism to C Gene) Therapy: The Example of the Genetic Immune Disorder Alain Fischer, MD, PhD Faculte de Medecine Hospital Necker-Enfantes Malades Paris, France Gene-Based Vaccines and Immuno Therapeutics Margaret Liu, MD Karolinska Institute Lafayette, California The Therapeutic Applications of Ribozymes and RNAi for AIDS John Rossi, PhD Chair and Professor, Division of Molecular Biology City of Hope National Medical Center Duarte, California Genomics, Medicine and Society And Session Chair: Gene-based Drug Design, Pharmacogenomics Francis Collins, MD, PhD Director, National Human Genome Research Institute Bethesda, Maryland Seven Membrane Spanning Receptors: How did we get here and where are we going? Robert J. Lefkowitz, MD James B. Duke Professor of Medicine, Duke University Medical Center Investigator, Howard Hughes Medical Institute The Future of Gene-based Medicine Session Chair: Francis Collins, MD, PhD Stem Cell Biology and Human Disease Stuart Orkin, MD Chairman, Department of Pediatric Oncology Dana-Farber Cancer Institute David G. Nathan Professor of Pediatrics, Harvard Medical School Investigator, Howard Hughes Medical Institute Systems Biology and Predictive, Preventive, and Personalized Medicine Lee Hood, MD, PhD President, Institute for Systems Biology Seattle, Washington Advancing the Revolution Through Genomic-based Medicine J. Craig Venter, PhD President, The Center for the Advancement of Genomics Rockville, Maryland The Genome and Human Rights Daniel Kevles, PhD Department of History, Yale University New Haven, Connecticut Closing Address - Humanity's Genes Sydney Brenner, PhD The Salk Institute La Jolla, California | |